Researchers from the University of Gdańsk have developed new forms of the well-known drug nimesulide, which significantly broadens the prospects of use. Nimesulide is a nonsteroidal anti-inflammatory drug (NSAID) that has been available by prescription for many years. A team of researchers from the Department of Physical Chemistry of the Faculty of Chemistry UG has developed a completely new – crystalline – form of the specific. The developed form of the drug has a much better solubility in water, which improves the absorption of the active substance and reduces the time of release of the drug in the body. In addition, there is potential antitumor, antimicrobial, antiviral activity and potential for use in the treatment of neurodegradative diseases.

Thanks to the new form of the drug, patients can benefit from new medicinal products that can be administered by other means than oral administration. Improving absorption will also allow for the use of lower doses or an increase in the time between doses. This discovery also benefits pharmaceutical companies, as the increased bioavailability of the drug substance translates into the amount of raw material needed to produce drugs. The cost of storing the drug will also decrease.

The invention of Gdańsk scientists was among the 20 final discoveries of the 10th edition of the competition “Eureka! DGP – discovering Polish inventions”. Scientists are planning to commercialise their invention, seeking patent protection at European level and scaling the production process to industrial scale.

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The article published on rynekzdrowia.pl; URL: https://www.rynekzdrowia.pl/Farmacja/Naukowcy-z-Uniwersytetu-Gdanskiego-opracowali-nowe-formy-znanego-leku-Zyska-nowe-wlasciwosci,247923,6.html

Magdalena Marynowska

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A student of law and international relations at the University of Warsaw, a multiple laureate of literary competitions, including poetry contests. I gained editorial experience as a leader of the social project “Nie Dotykaj Mnie,” where my main task was creating educational content for the project’s social media. I also had the opportunity to co-write the script for an educational film within the project. After the outbreak of the war in Ukraine, I worked as an Operations Specialist at the non-profit organization Student Initiative for Education, where my responsibilities included developing partnerships with cultural and entertainment centers throughout Poland and co-organizing events for Ukrainian children and youth. Privately, I am a PADI Advanced Open Water Diver.